In collaboration with faculty in Public Health and other colleges at OSU, we participate in a National Science Foundation funded project in the Predictive Intelligence for Pandemic Prevention (PIPP) initiative. Our grant is a Phase I Development Grant to tackle grand challenges in infectious disease pandemics through prediction and prevention. Our vision is that future cities will attenuate rather than amplify pandemic threats. Our rationale is that this is both necessary and sufficient to avert future pandemics. This grant is entitled PIPP Phase I: Coupling Predictive Intelligence with Adaptive Response to Engineer Pandemic-Resilient Cities. It has these main objectives: